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Facts: The brain is about 2% of bodyweight, but burns 20% of oxygen at rest Neurons cannot store energy; they rely on real time oxygen and ATP production from the cardiovascular and mitochondrial systems When metabolic output drops, cognition drops with it High cardiorespiratory fitness correlates to a 39% lower risk of dementia and a 36% lower risk of depression (VO2 max is a top modifiable predictor of dementia risk) Brain fog is often metabolic, not neurologic Every MET co